Cell surface antigen of encapsulated Staphylococcus epidermidis ATCC 31432.

Antibacterial activity of gemini quaternary ammonium salts.

A series of gemini quaternary ammonium salts (chlorides and bromides), with various hydrocarbon chain and spacer lengths, were tested. These compounds exhibited antibacterial activity against both Gram-positive and Gram-negative bacteria and were not mutagenic. The strongest antibacterial effect was observed for TMPG-10 Cl (against Pseudomonas aeruginosa ATCC 27853) and TMPG-12 Br (against Stap...

Vorinostat Pretreatment Enhanced Ciprofloxacin-Induced Antibacterial Activity

The mechanism of ciprofloxacin action involves interference with transcription and replication of bacterial DNA, which results in elevated oxidative stress, and bacterial cell death. Vorinostat was shown to induce oxidative DNA damage. In the current work, the possibility for interactive effect of vorinotat on ciprofloxacin-induced cytotoxicity against a number of reference bacteria was investi...

Enzyme-linked immunosorbent assay for detection of Staphylococcus epidermidis antibody in experimental S. epidermidis endocarditis.

The immune response against Staphylococcus epidermidis, as determined by an enzyme-linked immunosorbent assay, was evaluated in experimental S. epidermidis infections in rabbits. Antigens from 8 of 10 clinical S. epidermidis strains detected significant antibody production in five rabbits immunized with different strains of S. epidermidis and in five of six rabbits with experimental endocarditi...

epidermidis, ATCC 15305 Staphylococcus saprophyticus, ATCC 35663 Staphylococcus xylosus, ATCC 27840 Staphylococcus capitis subsp. capitis, ATCC 43809 Staphylococcus lugdunensis, ATCC 29970 Staphylococcus haemolyticus, ATCC 27844 Staphylococcus hominis subsp. hominis, and ATCC 43300 methicillin-resistant S. aureus (MRSA). Clinical isolates

Quantitatively predicting bacterial adhesion using surface free energy determined with a spectrophotometric method.

Bacterial adhesion onto solid surfaces is of importance in a wide spectrum of problems, including environmental microbiology, biomedical research, and various industrial applications. Despite many research efforts, present thermodynamic models that rely on the evaluation of the adhesion energy are often elusive in predicting the bacterial adhesion behavior. Here, we developed a new spectrophoto...